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Vitamin C is also important for healthy glutathione production

The column temperature was maintained at 55 C

Merkel cell carcinoma (MCC) is a rare, malignant neuroendocrine cutaneous tumor (Tello et al., 2018)

Animal studies used doses up to 1.1 mg per kilogram of body weight with no adverse effects observed

In contrast, the combination of chemoradiotherapy and immunotherapy with Gln metabolism inhibition may yield a more pronounced anti-tumor effect

Conversely, cancer cells were less sensitive to inhibitors of cystine uptake (for example, erastin) and the thioredoxin pathway (for example, auranofin, aurothioglucose and PX-12) (Fig