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Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity

DePalma AC, Raposa KA

Based on the crucial role that ROS play in the pathology and pharmacological treatment of a wide range of diseases, therapeutic strategies targeting the regulation of ROS homeostasis hold significant clinical value for revealing the molecular mechanisms of diseases, promoting drug development, and advancing personalized treatment

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GPx-1 and your SOD2 trait Given that SOD2 also helps to neutralise ROS generated during aerobic respiration, people carrying gene variants that reduce both SOD2 and Gpx-1 activity may be at greater risk of oxidative stress

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