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Important unresolved questions include whether BPC-157 reaches relevant central compartments under specific experimental conditions, whether observed CNS model effects depend primarily on vascular preservation, whether neurotransmitter changes are primary or secondary, and whether the brain-gut-axis hypothesis can be separated experimentally from general systemic effects

Statistics by two-sided unpaired t-tests compared to untreated empty vector transduced cells (g-i)

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Alternative Delivery Approaches Research continues into alternative delivery routes that could improve patient convenience and expand the clinical utility of peptide therapeutics

Interestingly, combination of both GHRH-mimetic and GHRP-2 was observed to apparently cause a 54-fold increase in pulsatile GH secretion compared to controls

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