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The placebo-adjusted LS mean (95% CI) change in body weight from baseline to week 36 for 45 mg was 8.2% (11.1 to 5.3%

In other words, berberine might help lower blood sugar levels in some people with type 2 diabetes

doi: 10.1097/CCE.0000000000000543

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Addiction patients with reduced cravings whose weight remains stable

We do not make a recommendation without an assessment that the benefits are likely to outweigh the risks, and we would always say take the smallest amount for the shortest period, consistent with what we hope to achieve from taking that medicine, Dr