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The primary hyperoxalurias are associated with overproduction and excessive urinary excretion of oxalate

In parallel, studies have reported modulation of early growth response-1 (EGR-1) expression and its regulatory partner NAB2, which are involved in cytokine signaling and early extracellular matrix formation during cellular response processes [2]

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for instance, myofibroblastic cancer-associated fibroblasts (myCAFs) promote CSC maintenance and metabolic adaptation, collectively enhancing drug resistance in breast cancer