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Severe epigastric pain radiating to the back may suggest pancreatitis, which is mentioned in Zepbound's prescribing information as a potential risk
Saturated fatty acids increase the amount of LDL (low-density lipoprotein), or "bad cholesterol," found in the blood (Schoeneck and Iggman 2021)
However, its important to consult a healthcare provider before making any changes to your medication regimen
The current KDIGO guidelines do not recommend SGLT2i for people in more advanced stages of CKD (eGFR 300 mg/g) and reduced progression of UACR in people with macroalbuminuria when compared with placebo
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