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But according to Hannah Cohan, a board-certified nurse practitioner with the Medical Offices of Manhattan, Its safer to explore other weight loss options, such as Zepbound (tirzepatide) or Ozempic (semaglutide), which can be used alongside Wellbutrin without the same risk of serotonin-related complications. Qsymia (phentermine/topiramate) and Contrave (bupropion/naltrexone) without Wellbutrin may be safer options purely for weight management

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You Have Weight-Related Health Conditions If being overweight contributes to or exacerbates other health conditions, semaglutide may be considered as part of an overall treatment plan

Exp Mol Pathol (2019) 107:1248

Prior authorization requirements Even when Aetna covers Wegovy or Zepbound, you will almost certainly need prior authorization (PA)