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This class of drugs was first used to treat type 2 diabetes

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Use of dipeptidyl peptidase-4 inhibitors was associated with a lower risk of Parkinson's disease in diabetic patients

Allow longer rest between sets (2 to 3 minutes for compound lifts)

Shelf logic is being redesigned around satiety, metabolic alignment and alcohol moderation

In the SURPASS-2 trial published in the New England Journal of Medicine, participants treated with tirzepatide (5 mg, 10 mg, or 15 mg weekly) experienced reductions in fasting triglycerides from baseline over 40 weeks, with greater reductions generally seen at higher doses