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A 2022 paper in the International Journal of Molecular Sciences characterised effects on proliferative activity and inflammatory pathways in monocyte/macrophage THP-1 cell research (PMID 35408963)

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Under hyperglycemic conditions, exendin-4 partially restores cisplatin sensitivity in Ishikawa and HEC1B EC cells, with treatment performed at 10 nM for 48 h and accompanied by modulation of apoptosis-related proteins (183)

Figure 2 shows the process of discovering treatment-specific PD and omics biomarkers, followed by analytical verification and testing of the biomarkers in additional clinical and nonclinical studies for translational qualification

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Its use is considered illegal in many countries, and it is often sold on the gray market, where product quality and purity are not guaranteed, posing additional health risks