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Mechanisms encompass loss of subcutaneous fat that typically offers structural support along with downstream impacts on dermal fibroblasts and the extracellular matrix that control collagen and elastin turnover

Topical GHK-Cu (creams, serums, microneedling solutions) produces minimal systemic absorption

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Laboratory models show its potential for supporting connective tissue health and cellular regeneration

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Studies show that people on GLP-1 medications do lose some lean mass along with fat, similar to what happens with any form of calorie restriction