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Mathieu d'Argent E, Ravel C, Rousseau A, et al
Disruption of this axis, by either pharmacological inhibition or genetic ablation, leads to ferroptotic cell death
Free radicals can be a result of a variety of factors such as toxin exposure, stress, immune dysfunction, and poor nutrition but our body also produces free radicals naturally during cellular reactions
The mechanical stress can shear the molecules delicate structure, a process called denaturation
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