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Proc Natl Acad Sci U S A (2003) 100(25):151605.10.1073/pnas.2334159100 128 LaffitteANeiersFBriandL

Think of it as giving your system the tools it needs to do what its already capable ofjust more effectively

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doi: 10.3389/FIMMU.2021.739048/REFERENCE 83 SmithMJPastorLNewmanJRBConcannonP

But caloric restriction, combined with the reduced nutrient density of a smaller total food volume, creates conditions where B vitamins including B12 become limiting factors for mitochondrial energy production