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Both medications are GLP-1 receptor agonists, but Zepbound also targets the GIP receptor, which may offer additional benefits for weight loss and blood sugar control compared to Semaglutide GLP-1

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Supports Amino Acid Transport Across Cell Membranes*

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In the subgroup with lupus nephritis, there were also lower risks for both MACE (HR, 0.64) and for renal progression (0.70)