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Posteriormente, Ceccarelli (1987) utiliz el suero hiperosmolar 7 , Rittes, en 1995, us la fosfatidilcolina 8,9 y Salti, en 2008, emple fosfatidilcolina y desoxicolato de sodio, tanto para el tratamiento de adiposidades localizadas como para tratamiento no quirrgico de lipomas 10

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Pharmacokinetic Parameters Clinical Uses Type 2 diabetes mellitus Obesity management Cardiovascular risk reduction in patients with diabetes Nonalcoholic fatty liver disease (off-label, investigational) Adverse Effects Nausea and vomiting Diarrhea Pancreatitis (rare) Thyroid C-cell tumors (rodent studies) Injection site reactions (if injectable) Comparative Analysis MCQs GLP-1 receptor agonists primarily act on: a) Alpha cells b) Beta cells c) Delta cells d) Hepatocytes Answer: b) Beta cells These drugs increase insulin secretion in a: a) Continuous manner b) Glucose-independent way c) Glucose-dependent way d) Inhibited state Answer: c) Glucose-dependent way Which of the following is a known adverse effect of GLP-1 agonists

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