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In the SURMOUNT-1 study, a phase 3 clinical trial in obese patients, randomized participants in a 1:1:1:1 ratio to tirzepatide (5, 10, 15 mg) or placebo over 72 weeks, significant weight reductions were observed at 72 weeks: 15.0% for 5 mg, 19.5% for 10 mg, 20.9% for 15 mg, compared to 3.1% for placebo [18]

This durability distinguishes BPC-157 from symptomatic treatments that require ongoing use

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[1] The prolonged half-life also has implications for drug washout following discontinuation

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BMI 30 kg/m 2 ) of sleep quality, body composition, handgrip strength, quality-of-life, anxiety/depression