A significant linear relationship between sound pressure levels and the risk of hypertension has been reported in several studies, with higher noise levels being associated with an increased likelihood of developing hypertension 61
Nevertheless, it is noteworthy that, in the HARMONY 7 trial 10 which was a head-to-head comparison between liraglutide and albiglutide (but which was not powered for cardiovascular outcomes), the fall in HbA1c for liraglutide was 0.98% compared with 0.79% for albiglutide (p=0.085) whereas the weight decrease was 2.2 kg for liraglutide compared with 0.6 kg for albiglutide (p0.0001)
Clinical trials to support NDAs for marketing approval are typically conducted in three sequential phases, but the phases may overlap
In children or adolescents with GH deficiency, height growth may be possible under medical treatment
If you suspect you are experiencing side effects from your GLP-1 medication, you can report these through the MHRA Yellow Card scheme (www.mhra.gov.uk/yellowcard)
After the fourth visit you will need to be seen every 3 months for as long as you continue the medication