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When p53 transcriptional activity in response to 5-FU treatment was measured, the mRNA and protein levels of p21, which is a p53 target gene, were decreased in the GST WT -p53-expressing cells
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The results were consistent across populations and treatment regimens
This recent spike in notoriety creates the misconception that the short- and long-term side effects are unknown
Purine-based Ir(iii) complexes for sensing viscosity of endo-plasmic reticulum with fluorescence lifetime imaging microscopy
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