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2015;10(8):e0127815
Wegovys maintenance dosing is more limited (only 1.7mg and 2.4mg), restricting this crucial flexibility
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This means Reta may not only influence appetite and insulin sensitivity but also support increased basal metabolic rate and fat utilization in research models
The titration phase (first 1620 weeks) is focused on reaching the therapeutic dose while minimizing GI side effects, not on maximum weight loss which is why early results are often modest
To account for the clustering of sites, categorical outcomes were analyzed by a logistic generalized linear mixed effects model, while continuous outcomes were analyzed by generalized estimating equations
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