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Nature 464(7293):13571361 Edwards TL, Scott WK, Almonte C, Burt A, Powell EH, Beecham GW, Wang L, Zuchner S, Konidari I, Wang G, Singer C, Nahab F, Scott B, Stajich JM, Pericak-Vance M, Haines J, Vance JM, Martin ER (2010) Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease
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doi:10.1001/jama.2021.4788
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Once PDH is inhibited by pyruvate dehydrogenase kinase 4 (PDK4), pyruvate oxidation and the production of fatty acids are blocked, thus hampering ferroptosis and facilitating the development of cancers [36]
