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The coprimary endpoints of the trial were the percentage change in body weight and achieving a weight reduction of at least 5% at 68 weeks for semaglutide 2.4 mg versus placebo, assessed by intention to treat
Maintenance of appetite suppression, improved insulin sensitivity, and behavioral changes accumulate over time, supporting continued gradual weight reduction
Rhabdomyolysis associated with the use of tirzepatide
Low folate is associated with fatigue, mood changes, and increased risk of birth defects in pregnancy
Reductions in liver fat content were closely linked to decreases in body weight and abdominal pain and fat
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