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The standard guideline is that an opened vial of BAC water should be discarded after 28 days

The primary target would be the annulus fibrosus, which is the tough outer ring that tears during a herniation

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10.1159/000346968 19 EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies) (2015)

The premise underlying the leaky gut hypothesis is that physiologic stressors such as anxiety, intensive exercise, or dietary components such as emulsifiers increase intestinal mucosal paracellular permeability, enhancing entry of pathogenic bacteria and bacterial toxins into the systemic circulation, provoking systemic inflammation and triggering numerous diseases