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Sounni, N.E., Paye, A., Host, L
Is standard practice to assess tolerance, monitor for adverse events, and identify the minimum effective dose (MED) that produces measurable biological responses without unnecessary exposure
Hasani, M., Arabpour, Z., Hasani, M., Saeedi, A., & Khodabakhshi, A
10.1177/0962280210394459 35 ParraM.StahlS.HellmannH
doi: 10.3390/biom11111685 64 KirkleyK
The reported sequencing solution: get one pathway saturated and stable first, then layer the second on a fresh titration
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