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Importantly, it also involves the braingutimmunepain axis , a bidirectional network through which the central nervous system, gut, immune cells, and peripheral nerves communicate

We also considered the strength of the evidence (the magnitude of observed effects) and the consistency of findings across various studies or sources

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Sections 3, 4, 6 is summarized in Supplementary Table S2

(2020) 45(Suppl 1):1727