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Availability of Data and Material The model code and data sets will be shared with researchers submitting a research proposal approved by the independent review board

Both medications share similar side effectsmainly nausea, vomiting, and diarrheathough retatrutide shows slightly higher rates of gastrointestinal issues in early studies

The peptide stimulates the pancreas to release insulin only when blood glucose rises

Lyophilized MT-1 is stored at -20C for long-term storage and 2-8C for short-term use within 30 days

Aggressive shaking introduces air bubbles and can denature the peptide

Results in trial reports (primary trial results and subsequent secondary publications), and their accompanying Additional file 1, were used as the primary source of information