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Photosynth Res 89:225245 Mieda T, Kabuta Y, Rapolu M, Motoki T, Takeda T, Yoshimura K, Ishikawa T, Shigeoka S (2004) Feedback inhibition of spinach L-galactose dehydrogenase by L-ascorbate

Its synthesis is catalyzed by the enzyme encoded by the immune response gene 1 (IRG1), also named ACOD1, which facilitates the conversion of cis-aconitic acid [15]

Also, alteration in the factors influencing successful differentiation and proliferation of melanocytes due to oxidative stress, such as altered Wnt signaling, may also render susceptibility to vitiligo