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One of these nucleophilic species is glutathione, a tripeptide that is synthesized in the cytosol from glutamic acid, cysteine and glycine, that exists in thiol-reduced (GSH) and disulfide-oxidized (GSSG) forms, with the former representing around 98% of intracellular glutathione under physiological conditions 29

Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial

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