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NICE specifically advises against initiating the following medications for chronic primary pain (including fibromyalgia): antiepileptics (including gabapentinoids such as pregabalin and gabapentin), opioids, paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, corticosteroids, and antipsychotics

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The Transdermal Delivery Question and Expert Perspectives One key question with any patch is whether its ingredients can actually be absorbed through the skin and have effects throughout the body

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