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Efficacy for blood sugar (HbA1c) In clinical trials, metformin reduced HbA1c by 1%-2% or 11-22 mmol/mol and fasting blood glucose (FBG) by 2-3 mmol/L in patients with type 2 diabetes
Antioxidant defense: GHK-Cu upregulates genes encoding antioxidant enzymes including superoxide dismutase (SOD) and glutathione-S-transferase, strengthening the cells defenses against oxidative damage from UV radiation, environmental pollution, and endogenous metabolic byproducts
DSIP mechanism is multifaceted and not fully elucidated
Such alterations have been noted in individuals with type 2 diabetes, obesity, and metabolic syndrome, though the precise mechanisms remain an active area of research
There are two transketolase-related genes in the human genome
IGFBP-3 (IGF binding protein 3)
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