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Chemical Name: DSIP (Delta Sleep-Inducing Peptide) Molecular Formula: C35H48N10O15 Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (9-amino acid neuropeptide) Research Applications: Sleep cycle regulation studies Circadian rhythm modulation research Stress response and cortisol pathway analysis Pain perception and analgesic mechanism studies Hypothalamic-pituitary axis research Sleep architecture and REM cycle protocols Neuroendocrine system interaction studies Product Specifications: Form: Lyophilized powder Purity: High purity research grade Molecular Weight: 848.8 g/mol Storage: Store at -20C, protect from light and moisture Reconstitution: Use bacteriostatic water (not included) Stability: 24 months when stored properly, 30 days once reconstituted Research Background: DSIP is a naturally occurring neuropeptide originally isolated from the cerebral venous blood of rabbits in sleep-induced states

Yant LJ, Ran Q, Rao L, et al

The benzyl alcohol preservative inhibits bacterial growth, extending the usable life of your reconstituted solution

Again at the mRNA level, chronic treatment of rats with nicotine produces an elevated expression of ubiquitin-conjugating enzymes, proteasome regulatory and catalytic subunits and DUBs in the prefrontal cortex whereas their level is decreased in the medial basal hypothalamus (Kane et al., 2004)

J Neurochem 103(1):1737 Uversky VN, Lee HJ, Li J, Fink AL, Lee SJ (2001a) Stabilization of partially folded conformation during alpha -synuclein oligomerization in both purified and cytosolic preparations

Reports the unusual structure of an -integrin transmembrane domain and describes the membrane insertion of this domain