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7.3 NETosis-related tubular injury NETosis is a specialized form of neutrophil cell death where neutrophils extrude their nuclear chromatin and granular proteins to form neutrophil extracellular traps (NETs) (218)

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Exercise capacity was determined by a single maximal exercise test to voluntary fatigue on a motorized treadmill (Exer 3/6, Columbus Instruments) in females [Young ( n = 10), Old Con ( n = 17), and Old mAb ( n = 22)] and males [Young ( n = 10), Old Con ( n = 9), and Old mAb ( n = 9)]

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Partial agonists typically produce less receptor desensitization and internalization than full agonists because they generate a less intense signaling response that triggers weaker recruitment of beta-arrestins and GRK-mediated receptor phosphorylation