The microbiota modulates GLP-1 secretion through microbial metabolites
[2] [3] NICE guidance (NG28) recommends GLP-1 receptor agonists for adults with type 2 diabetes who have inadequate glycaemic control despite optimal management with metformin and other oral agents, particularly when significant weight loss would be beneficial
However, given the close association between obesity and OSA, as well as the effectiveness of other forms of weight loss in combating OSA, incretin-based therapies hold promise as a therapeutic option for the management of obesity-related OSA
Rotating injection sites between abdomen, thigh, and upper arm prevents lipohypertrophy and maintains consistent absorption
It is also beneficial for those managing type 2 diabetes or prediabetes, as it offers both weight loss and blood sugar regulation benefits
Dont hesitate to take the first step towards achieving your weight loss goals