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It creates pressure, bloating, and sulfur burps that many GLP-1 users describe as one of their worst side effects
Dosing schedule follows a gradual escalation to minimise gastrointestinal side effects: Starting dose : 2.5 mg once weekly for four weeks Maintenance dose : Increase to 5 mg once weekly after the initial four weeks Dose escalation : If additional glycaemic control or weight loss is needed, the dose may be increased in 2.5 mg increments at four-week intervals Maximum dose : 15 mg once weekly The injection should be administered subcutaneously in the abdomen, thigh, or upper arm , rotating injection sites to reduce the risk of lipodystrophy
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Regarding the cardiovascular mortality rate in patients with liraglutide, it was lower compared to placebo (RR 0.78
And one of our registered dietitians weighs in on Nooms approach
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