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Butylated hydroxyanisole regulates ARE-mediated gene expression via Nrf2 coupled with ERK and JNK signaling pathway in HepG2 cells: ACTIVATION OF Nrf2-ARE SIGNALING BY BHA AND MAPK

Reasoning that the enzymes encoded by these genes could be responsible for the utilization of l-carnitine and its conversion to BB (Figure 7C), we used comparative genomics tools to identify 3 other organisms that contain the caiTABCDE gene operon (Supplemental Figure 5), and assessed their ability to consume l-carnitine and produce BB (Figure 8)

Namely, carbamoyl phosphate synthetase 2 (CPS 2) can accept the amide group from glutamine to generate carbamoyl phosphate, a rate-limiting step in pyrimidine synthesis

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TREATMENT TIME: Treatment time is 1 hour After care

ZR2024QH068) and the Research Fund for Lin Hes Academician Workstation for New Medicine and Clinical Translation at Jining Medical University (No