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Upregulation of antioxidant enzyme expression or activity Antioxidant enzymes, such as superoxide dismutase (SOD), glutathione peroxidase (GPx), and glutathione reductase (GR), convert reactive oxygen species (ROS) into harmless substances, thereby reducing cellular oxidative stress and mitigating radiotherapy-induced inflammation 28

Moderate nutrient restriction of beef heifers alters expression of genes associated with tissue metabolism, accretion, and function in fetal liver, muscle, and cerebrum by day 50 of gestation

Escudier S, Engel E, Pierce S, Keating M, Andreeff M

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