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Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus (NCT00672074)

(106) included seven randomized, placebo-controlled trials that exclusively enrolled individuals with high blood pressure, i.e., with systolic blood pressure (SBP) 140 mm Hg and/or diastolic blood pressure (DBP) 90 mm Hg

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The medication crosses the placenta and animal studies showed fetal harm, though human data remains limited