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B12 is one of 8 B vitamins
Its elimination half-life is approximately 159195 hours (roughly 6.58 days), achieved by a fatty-acid side chain that binds reversibly to serum albumin
De Luca, A
2.4 CHAC1-mediated regulation of stem cell fate and development via NOTCH1 signaling Given the central role of glutathione in maintaining redox balance, its levels are a key determinant of stem cell fate
humidity exposure during storage allows water vapor to initiate slow hydrolysis even without reconstitution
Together, these advances transform LYTACs from a receptor-dependent concept into a versatile degradation platform capable of overcoming heterogeneity in receptor expression, minimizing off-target effects, and addressing multiple resistance mechanisms
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