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This redox imbalance promotes mitochondrial DNA damage, lipid peroxidation, and activation of apoptotic pathways, ultimately contributing to myofibrillar disorganisation and interstitial fibrosis (73)

Enhanced extracellular matrix deposition has also been observed, indicating regulated synthesis and assembly of key structural proteins such as collagen and elastin, which are essential for restoring tissue strength and elasticity in experimental systems

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Retrieved from DOI: 10.1097/01.NURSE.0000441246.36711.66 Wittmer Rejuvenation Clinic

Leyden J, Dunleavy K