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This study presents a novel DEC that concurrently targets oxidative stress (via ergothioneine and tocopheryl glucoside) and glycation (via decarboxy carnosine and naringin), demonstrating its efficacy in suppressing melanogenesis across clinical, cellular, and 3D skin models
They then performed 1:1 propensity score matching to create clinically comparable groups in three key analyses
The investigators evaluated tendon-explant outgrowth, fibroblast proliferation (MTT assay), cell survival under hydrogen peroxide oxidative stress, and fibroblast migration (transwell filter migration assay) in the presence and absence of BPC-157
2020 , L- ,
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Details of the work were published in 2014
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