They weren't shy about it
Gastrointestinal side effects are the most frequently reported adverse reactions during initial GLP-1 treatment, though their severity and occurrence vary considerably among individuals and products
Reduced caloric intake due to appetite suppression may lead to insufficient energy consumption, particularly during the initial treatment phase
Other peptides, like semaglutide, tirzepatide, and liraglutide, are proven treatments for obesity
1 Introduction Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by impaired hypothalamic development and function with an estimated incidence of 1 per 20,000 newborns ( Patients with PWS experience complex nutritional, neurodevelopmental, metabolic and behavioral changes that drive obesity development ( Obesity management in PWS typically includes a calorie-restricted diet, strict control of food access, regular physical activity and behavioral interventions ( 2 Case series 2.1 Patient 1 A 28-year-old female with PWS, resulting from uniparental disomy, was evaluated at our Endocrinology Unit
Physician 94 , 820827 (2016)