Retatrutide is an investigational weight management medicine currently undergoing clinical development
This triple-agonist profile separates it from dual agonists like tirzepatide, which targets only GLP-1 and GIP
The food and wellness industry is already responding to this shift, rapidly expanding high-fiber and high-protein offerings and developing products formulated to support satiety with ingredients such as protein isolate, glutamine, creatine, probiotics, polyphenols, and fiber
Study Selection The study protocol was preregistered on OSF on December 13, 2024 ( This systematic review followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines (Page et al., 2021)
Archives Oral Biol
GLP-1 receptor agonists enhance insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite