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Name: step 1 trial semaglutide 2.4 mg weight loss nejm 2021 in Patients with Obesity-Related Heart Failure and Type 2 Diabetes Weight regain and cardiometabolic effects
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Shin Y-K, Egan JM

There is no published long-term human safety data, no completed RCT, and the most-cited theoretical concern remains angiogenesis in the context of undiagnosed cancer