reconstituted at 2-8 C, up to 12 weeks

Race and ethnicity Patients were classified based on self-reported race and ethnicity that were mapped to standards as Hispanic, Multiracial, White only, Black only, or Other Amputation An encounter or billing diagnosis with ICD-10-CM code Z89.2*, Z89.6*, S78.011A, S98.011A, S78.012A, S98.012A, S78.019A, S98.019A, S78.021A, S98.021A, S78.022A, S98.022A, S78.029A, S98.029A, S78.111A, S98.111A, S78.112A, S98.112A, S78.119A, S98.119A, S78.121A, S98.121A, S78.122A, S98.122A, S78.129A, S98.129A, S78.911A, S98.131A, S78.912A, S98.132A, S78.919A, S98.139A, S78.921A, S98.141A, S78.922A, S98.142A, S78.929A, S98.149A, S88.011A, S98.211A, S88.012A, S98.212A, S88.019A, S98.219A, S88.021A, S98.221A, S88.022A, S98.222A, S88.029A, S98.229A, S88.111A, S98.311A, S88.112A, S98.312A, S88.119A, S98.319A, S88.121A, S98.321A, S88.122A, S98.322A, S88.129A, S98.329A, S88.911A, S98.911A, S88.912A, S98.912A, S88.919A, S98.919A, S88.921A, S98.921A, S88.922A, S98.922A, S88.929A, or S98.929A or a procedure with ICD-10-PCS code 0Y6[23478CDFGHJ]* or 0X6[012389BCDF]* Limitations Because medication dispense information relies upon third-party queries operating in the U.S

GLP-1 receptor agonists like semaglutide (Wegovy), tirzepatide (Zepbound), and liraglutide (Saxenda) work through multiple mechanisms to improve blood sugar control and promote weight loss
These are among the leading causes of preventable, premature death
EMA refused authorization in 2014 for reasons of benefit-risk ratio deemed insufficient in the European population
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