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El ensayo SUSTAIN-6 demostr una reduccin del 26 % en eventos cardiovasculares mayores (MACE) un compuesto de muerte cardiovascular, infarto de miocardio no fatal y accidente cerebrovascular no fatal en pacientes con diabetes tipo 2 y alto riesgo cardiovascular

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In the STEP trials, participants taking semaglutide lost 10-22% of baseline body weight over 68 weeks, compared to 2-3% in the placebo groups

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10.1007/BF00252263 Diabetologia 31 CollinsJ