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In contrast, single injection of Tregs or IL-10 overexpressing engineered T cells promoted gene expression of chemokines/cytokines in microglia (Ccl2, Ccl7, and Cxcl10), regulated the chemotactic behavior of microglia and neural stem cells, promoted angiogenesis, and was speculated to contribute to the repair of ischemic injury (95)

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20 to 100 healthy volunteers or patients with the condition