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A similar observation has been made in a study, where 77 the diluted form of antisera against SARS-CoV spike protein has been found to promote ADE and enhanced apoptosis at the same time, while neutralizing antibodies against SARS-CoV neutralized infection 55

However, owing to the lack of paracrine regulation of key components of the neurovascular unit (NVU), such as astrocytes and peripheral cells, maintaining the polarization characteristics and functional protein expression of the BBB for a long period of time is difficult (Qi et al., 2023

MahmoudianDehkordi S, Ahmed AT, Bhattacharyya S, Han X, Baillie RA, Arnold M et al (2021) Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression

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