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Research suggests that it is helpful for those prone to both constipation and diarrhea

The authors thank Chunyan Zhang for her meticulous technical support throughout the preparation of this manuscript

The high dose of cyanocobalamin is generally well-tolerated due to the vitamins water-soluble nature and efficient excretion of excess amounts

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Only after successful validation across these sequential stages could microbiome-guided precision endocrinology become a realistic and actionable clinical objective