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Data for patients with ALF were obtained from the NCBI Gene Expression Omnibus (GEO, We downloaded the GSE14668 and GSE96851 datasets, which were derived from the GPL570 platform (Affymetrix Human Genome U133 Plus 2.0 Array)[19, 20]

Data were analyzed by two-way ANOVA, followed by multiple comparisons adjusted with the Sidk-Holm correction

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West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, Walsh MC, Choi Y, Shadel GS, Ghosh S (2011) TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

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As such, the side chain of E14 Cagri rotates slightly downwards and reduces the number of H-bonds with R17 Cagri