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However, a small percentage of the medicationusually about 5% to 10%is processed through a different pathway involving a specific enzyme
Preclinical studies suggest that GLP-1 receptor signaling may also influence intestinal epithelial turnover, oxidative stress, and gut barrier integrity
Lancet Diabetes Endocrinol 5 , 341354 (2017)
While the findings for GLP-1 RAs have a more complex interpretation, the fact that use of SGLT2is is probably cost-effective in our analyses has important policy implications
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