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Folsom et al, 1998

For instance, nitrofuran derivatives such as C-176 and H-151 covalently bind to Cys91 of stimulator of interferon genes (STING), thereby preventing its S-palmitoylation and subsequent multimerization, a mechanism exploited for the treatment of autoinflammatory disease [184, 185]

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The Mthfr / mice were with none MTHFR enzyme activity in all tissues, whereas the Mthfr +/ showed 60% residual activity, similar to the value observed in patients homozygous for the C667T polymorphism 40