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Also studied for inflammation modulation, angiogenesis, and neural tissue protection
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ICH Q2(R2) Validation of analytical procedures Scientific guideline. EMA
For those sensitive to needles, a numbing cream may be applied to the injection site to reduce any discomfort during the procedure
But the mechanism is well-characterized and the target (NNMT in adipose tissue) is a legitimate pathway for visceral fat reduction
Whether this tradeoff makes sense depends on individual priorities, including needle aversion, convenience requirements, and budget considerations
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